This disease has had a number of names over the past few years; Nordic breed alopecia, Pseudo- Cushings or congenital adrenal hyperplasis-like syndrome, A-Typical Cushings, CRFA (Canine Recurrent Flank Alopecia). No matter what the disease is called, it is an endocrine dermatosis and cause bilateral alopecia affecting mostly young adult dogs. Most frequently affected breeds include Chow, Pomeranian, Alaskan Malamute, Siberian Husky , Samoyedo although it has been described in the Poodle. The condition is characterized by adult onset symmetrical alopecia (hair loss) usually by the age of 3 years. First the long primary hairs go leaving a fuzzy puppy-like coat but eventually that goes also.
Dermatonin is a constant-release Melatonin Implant for canines with Alopecia X and Seasonal Flank Alopecia. The product comes in a Gas sterilized, Pre-loaded, Disposable, Implanting Device to ensure the safety and wellness of your canine patients.
Melatonin has been researched by veterinarians across the United States, as well as Canada for its use in controlling the symptoms associated with Alopecia X and Seasonal Flank Alopecia. Dermatonin puts melatonin in an implant form, eliminating the need for twice daily dosing and provides a consistent level of melatonin for maximum effectiveness.
Although there is not a lot of research veterinary dermatologist are currently engaged in "clinical trials" using constant-release melatonin implants for the treatment of symptoms associated with Alopecia-X.
For more information you may consult Current Veterinary Therapy XIII, pages 546-549 (article entitled "Melatonin Therapy for Canine Alopecia), or the author of the article Dr. Manon Paradis, Professor of Veterinary Dermatology, Veterinary Medicine, University of Montreal.
TO ORDER and pricing please have your veterinarian call:
Butler Schein at (888) 691-2724 MWI Veterinary Supply at 800-824-3703 MarketLink for AHAA members 888-722-2242 Pricing only e-mail: firstname.lastname@example.org.
Shelf-life is 2 years, refrigeration (not required/but recommended), the Dermatonin must be keep out of direct UV light. Each Melatonin implant consistently administers melatonin for approximately 4 to 6 months. Implant device uses a 12 gauge needle and is administered subcutaneously, similar to microchips. (For more information and instruction please see theDESCRIPTION PAGE)
Melatek currently recommends the following dosage ofDermatonin:
· Dogs under 25 lbs: One 8.0 mg melatonin implant
· Dogs over 25 lbs: One 12.0 mg melatonin implant
· Dogs over 50 lbs: One 18.0 mg melatonin implant
Cats all weight : One 18.0 mg melatonin implant
Sorry we did not list the pricing on the web page, we are only selling only to Veterinarians. Respecting the veterinarians pricing structure, we would like to not make the pricing public knowledge. NOTE: Veterinarians and their clinics can get pricing direct from Melatek, by sending an e-mail to: customer service @ melatek.net
Dermatonin:(Melatonin Implant for your canine) Trunk alopecia has always been frustrating to practitioners because it may encompass several conditions many of which are historically without standard treatments. The conditions which make up the term Alopecia X are often unexplained and lumped in to a group which are essentially too difficult to treat or untreatable. In the fall of 2004 I was presented with a Boxer named Avalanche with seven centimeter areas of alopecia on both sides of the lateral thorax. After scrapes, cultures, blood work and biopsies it was determined to be seasonal alopecia. Having had extensive experience with Ferretonin ( 5.4 mg melatonin implant) in hyper adrenal ferrets, I was happy to give Dermatonin (18.0mg melatonin implant) a try in this Boxer. By the time the implants were administered the area was patchy from shoulders to the wing of the ileum. The Dermatonin started to work within 30 days and at eight weeks the hair cover was very good. We have continued with the implants ever 4-6 months and the alopecia has never returned. The clients love the way Avalanche looks and we have not experienced any side effects to date. I think Dermatonin gives me option for this type alopecia, I would definitely recommend this product to other Veterinarians. Dr. Joseph E Kelley, DVM
In veterinary dermatology, melatonin implants (Dermatonin) have been used to treat dogs with recurrent flank alopecia, a disease characterized by episodes of bilaterally symmetric hair loss in the thoracolumgaar region that may occur on a recurrent basis. The majority of dogs have an onset of alopecia between November and March, suggesting that the pathogenesis of the disease may be a genetically influenced deficiency of melatonin.
One study conducted treated 9 dogs with recurrent flank alopecia 2 months prior to the next expected episode with 2 subcutaneous Dermatonin injections (12 mg of melatonin). All of the dogs reacted great to the melatonin implant (Dermatonin) none of the doges experienced the large area of alopecia as they had in the previous years. Since this study, several veterinary dermatologists have used melatonin in recurrent flank alopecia to prevent recurrence or shorten the durations of the alopecic episode.
PLEASE NOTE: Every effort has been made to ensure the accuracy of the information published. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the product label or package insert. To contact Melatek 877-635-2835.
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