Melatonin Implants

ALOPECIA X IN DOGS

This disease has had a number of names over the past few years; Nordic breed alopecia, Pseudo- Cushings or congenital adrenal hyperplasis-like syndrome, A-Typical Cushings, CRFA (Canine Recurrent Flank Alopecia).  No matter what the disease is called, it is an endocrine dermatosis and cause bilateral alopecia affecting mostly young adult dogs.  Most frequently affected breeds include Chow, Pomeranian, Alaskan Malamute, Siberian Husky , Samoyedo although it has been described in the Poodle.  The condition is characterized by adult onset symmetrical alopecia (hair loss) usually by the age of 3 years.  First the long primary hairs go leaving  a fuzzy puppy-like coat but eventually that goes also.

 Dermatonin is a constant-release Melatonin Implant for canines with Alopecia X and Seasonal Flank Alopecia. The product comes in a Gas sterilized, Pre-loaded, Disposable, Implanting Device to ensure the safety and wellness of your canine patients. 

Melatonin has been researched by veterinarians across the United States, as well as Canada for its use in controlling the symptoms associated with Alopecia X and Seasonal Flank Alopecia.  Dermatonin puts melatonin in an implant form, eliminating the need for twice daily dosing and provides a consistent level of melatonin for maximum effectiveness.

Although there is not a lot of research veterinary dermatologist are currently engaged in "clinical trials" using constant-release melatonin implants for the treatment of symptoms associated with Alopecia-X.

TO ORDER and pricing please call: 

 Butler Schein at (888) 691-2724 
 MWI Veterinary Supply at 800-824-3703
MarketLink for AHAA members 888-722-2242 
TW Medical at 888-787-4483

 New: The Apothecary Shop (877) 792-7684
Pricing only e-mail:  customerservice@melatek.net.

Shelf-life is 2 years, refrigeration (not required/but recommended),  the Dermatonin must be keep out of direct UV light.   Each Melatonin implant consistently administers melatonin for approximately 4 to 6 months. Implant device uses a 12 gauge needle and is administered subcutaneously, similar to microchips. (For more information and instruction please see the  DESCRIPTION PAGE)

Melatek currently recommends the following dosage of Dermatonin: 

·         Dogs under 25 lbs: One 8.0 mg melatonin implant 

·         Dogs over 25 lbs:  One 12.0 mg melatonin implant

In veterinary dermatology, melatonin implants (Dermatonin) have been used to treat dogs with recurrent flank alopecia, a disease characterized by episodes of bilaterally symmetric hair loss in the thoracolumgaar region that may occur on a recurrent basis. The majority of dogs have an onset of alopecia between November and March, suggesting that the pathogenesis of the disease may be a genetically influenced deficiency of melatonin.

One study conducted treated 9 dogs with recurrent flank alopecia 2 months prior to the next expected episode with 2 subcutaneous  Dermatonin injections (12 mg of melatonin). All of the dogs reacted great to the melatonin implant (Dermatonin) none of the doges experienced the large area of alopecia as they had in the previous years.  Since this study, several veterinary dermatologists have used melatonin in recurrent flank alopecia to prevent recurrence or shorten the durations of the alopecic episode.